Evaluation of cephalometric characteristics and skeletal maturation of the cervical vertebrae and hand-wrist in girls with central precocious puberty
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°¼ºÅ ( Kang Sung-Tae ) - Yonsei University College of Dentistry Department of Orthodontics
ÃÖ¼ºÈ¯ ( Choi Sung-Hwan ) - Yonsei University College of Dentistry Department of Orthodontics
±è°æÈ£ ( Kim Kyung-Ho ) - Yonsei University College of Dentistry Department of Orthodontics
ȲÃæÁÖ ( Hwang Chung-Ju ) - Yonsei University College of Dentistry Department of Orthodontics
Abstract
Objective: This study aimed to evaluate the differences in cephalometric characteristics and skeletal maturation in girls with central precocious puberty (CPP) via lateral and hand-wrist radiographs. We also aimed to identify the indicators that are most effective for determining skeletal maturity in these patients.
Methods: The study included 70 Korean girls (mean age, 8.5 ¡¾ 0.5 years) diagnosed with CPP at the Department of Pediatrics, and 48 normal healthy age-matched girls who visited the Department of Orthodontics and had no history of hormone treatment or growth problems. Skeletal maturation was evaluated using lateral cephalometric and hand-wrist radiographs using cervical vertebrae maturation indicators (CVMI) and skeletal maturity indicators (SMI).
Results: The mean mandibular plane angle was smaller in the CPP group than in the control group (35.8¡Æ ¡¾ 4.9¡Æ vs. 39.0¡Æ ¡¾ 6.5¡Æ), resulting in greater posterior facial height (p = 0.003). SMI was significantly greater in the CPP group (3.5 ¡¾ 1.4 vs. 2.0 ¡¾ 1.0) than in the control group (p = 0.001) and was significantly associated with CPP (r = 0.492; p = 0.001), whereas CVMI was not.
Conclusions: In comparison with the control group, the CPP group exhibited a smaller mandibular plane angle, greater posterior facial height, and greater skeletal maturation. SMI may be more suitable than CVMI for determining skeletal maturation in CPP. Hand-wrist radiography is recommended in addition to lateral cephalogram for predicting growth in girls with CPP.
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Cephalometrics; Skeletal maturation; Central precocious puberty; Hand-wrist
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